![]() ![]() Both rat-specific gene arrays and qPCR will be performed focusing on genes already implicated in oxidative stress responses and cardiac disease. after 90 days of simulated weightlessness (HU) and after 90 days recovery from 90 days of HU. In this study, we will first conduct general analyses of three-month old male and female animals, focusing on two key long-duration time points, (i.e. ![]() The central hypothesis of our study is that long duration simulated weightlessness and subsequent recovery causes select and persistent changes in gene expression and oxidative defense-related pathways. Our current study aims to determine the molecular mechanisms that underlie these cardiac changes in response to spaceflight. Tahimic, Candice Steczina, Sonette Terada, Masahiro Shirazi-Fard, Yasaman Schreurs, Ann-Sofie Goukassian, David Globus, Ruth ![]() Responses of Cardiac Tissue to Simulated Weightlessness ![]()
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